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Lövebrant, Johanna, 2013. Surgical stress response in dogs diagnosed with pyometra undergoing ovariohysterectomy. Second cycle, A2E. Uppsala: SLU, Dept. of Clinical Sciences

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Abstract

The aim of this study was to investigate the intraoperative surgical stress response in dogs undergoing ovariohysterectomy and to compare acepromazine and medetomidine as premedications. 15 dogs diagnosed with pyometra were used in this study. Blood pressure and heart rate were used as parameters to measure surgical stress response. The surgery was divided into four phases. Phase 0 was the period 10 minutes before the skin incision, phase 1 was skin incision and opening of abdomen, phase 2 was manipulation of uterine horns, ligation and transection of mesovarium and phase 3 was ligation of cervix, removal of organs and closing the abdomen.

The results showed that phase 2 was the most intense phase of surgical stress, regardless of which premedication the dogs received.

When acepromazine and medetomidine were compared the results showed that within phase 3, all dogs that were given medetomidine had higher blood pressure compared to dogs that were given acepromazine.

The dogs that were given acepromazine had higher heart rate than the dogs that were given medetomidine in phase 0, phase 2 and phase 3.

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Målet med denna studie var att undersöka intraoperativ kirurgisk stress hos hundar som genomgår ovariehysterektomi och att jämföra acepromazin och medetomidin som premedicinering. 15 hundar som diagnosticerats med pyometra användes i denna studie. Blodtryck och hjärtfrekvens användes som parametrar för att mäta den kirurgiska stressen. Kirurgin delades in i fyra faser. Fas 0 var perioden 10 minuter före hudsnittet, fas 1 var hudsnittet och öppnandet av buken, fas 2 var manipulation av livmoderhornen och ligering av mesovariet och fas 3 var ligering av cervix, borttagande av organ och stängning av buken.

Resultatet visade att fas 2, ligering av mesovarie och borttagande av äggstockar, var den mest intensiva fasen av kirurgisk stress, oavsett vilken premedicinering hundarna fick.

När acepromazin och medetomidin jämfördes visade resultaten att inom fas 3, ligering av cervix, borttagande av organ och stängning av buk, hade alla hundar som fått medetomidin högre blodtryck i jämförelse med hundar som fått acepromazin.

Hundar som fick acepromazin hade högre hjärtfrekvens än hundar som fick medetomidin i fas 0, fas 2 och fas 3.

Main title:Surgical stress response in dogs diagnosed with pyometra undergoing ovariohysterectomy
Authors:Lövebrant, Johanna
Supervisor:Höglund, Odd
Examiner:Ljungvall, Ingrid
Series:Examensarbete / Sveriges lantbruksuniversitet, Fakulteten för veterinärmedicin och husdjursvetenskap, Veterinärprogrammet
Volume/Sequential designation:2013:69
Year of Publication:2013
Level and depth descriptor:Second cycle, A2E
Student's programme affiliation:3050A Veterinary Medicine Programme (admitted before July 1, 2007) 330 HEC
Department:(VH) > Dept. of Clinical Sciences
Keywords:Surgical stress response, Pyometra, Surgery, Acepromazine, Medetomidine, kirurgisk stress,, pyometraoperation, acepromazin, medetomidin
URN:NBN:urn:nbn:se:slu:epsilon-s-2480
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-s-2480
Subjects:Veterinary science and hygiene - General aspects
Animal diseases
Language:English
Deposited On:03 Jul 2013 11:42
Metadata Last Modified:03 Jul 2013 11:42

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