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Leijonflycht, Carolina, 2011. Refugia som metod för att minska utvecklingen av anthelmintikaresistens hos får. First cycle, G2E. Uppsala: SLU, Dept. of Biomedical Sciences and Veterinary Public Health (until 231231)



Anthelmintic resistance is a major problem in sheep husbandry all over the world. One way to
slow down the development of anthelmintic resistance is to keep part of the parasite
population in refugia (unexposed to drugs) which will maintain the genes for susceptibility
within the population. Climate, type of parasite and drenching regimes effect the size of the
refugia. Dilution of resistant with susceptible parasites, targeted treatment and targeted
selective treatment are all management strategies that employ refugia. Dilution is possible but
complicated. Targeted treatment means not drenching when there are few parasites in refugia
as this selects for resistance. Targeted selective treatment means only drenching animals that
need treatment. FAMACHA© has turned out to be an effective method to pick out the
animals which suffer from an infection with H. contortus. To use daily weight gain as an
indicator of which animals to treat is effective but costly. Five point check© needs
development and evaluation to be a useful alternative. The methods need to be simple, cheap
and functional in order to be used by farmers. There is also a need for foregoers among the
farmers that can show the others that the new methods work and do not lead to production
loss and a worsened animal health. Refugia delay the development of anthelmintic resistance
– it does not stop it.

Main title:Refugia som metod för att minska utvecklingen av anthelmintikaresistens hos får
Authors:Leijonflycht, Carolina
Supervisor:Höglund, Johan and Tydén, Eva
Series:Veterinärprogrammet, examensarbete för kandidatexamen / Sveriges lantbruksuniversitet, Institutionen för biomedicin och veterinär folkhälsovetenskap (t.o.m. 2015)
Volume/Sequential designation:2011:50
Year of Publication:2011
Level and depth descriptor:First cycle, G2E
Student's programme affiliation:VY002 Veterinary Medicine Programme 330 HEC
Supervising department:(VH) > Dept. of Biomedical Sciences and Veterinary Public Health (until 231231)
Keywords:får, anthelmintikaresistens, refugia, riktad selekterande behandling, gastrointestinala nematoder
Permanent URL:
Subject. Use of subject categories until 2023-04-30.:Veterinary science and hygiene - General aspects
Pests of animals
Miscellaneous animal disorders
Deposited On:11 Apr 2011 09:25
Metadata Last Modified:20 Apr 2012 14:18

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