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Andersson, Malin, 2011. African swine fever in Uganda : description of a recent outbreak and possible differential diagnoses. First cycle, G2E. Uppsala: SLU, Dept. of Biomedical Sciences and Veterinary Public Health

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Abstract

This study had two different aims. The main aim was to investigate the dynamics and impact of African swine fever (ASF) on a farm in Uganda during a recent outbreak through a case study. The second aim was to estimate the presence of two important differential diagnoses of ASF: Classical swine fever (CSF) and Porcine Reproduction and Respiratory syndrome (PRRS).
The field and laboratory based case study of the farm level dynamics of ASF virus during a recent outbreak (October-December 2010) on a farm in the district of Mityana, Uganda, was conducted, using interviews, ELISA and RT-PCR. The financial impact on the farm was also estimated. The impact of the outbreak was profound. The farmer lost approximately over half of the population of pigs; mainly adults and newborn piglets were affected. Weaners and older piglets survived to a relatively larger extent. The outbreak spread between pens and units probably via direct and indirect contact. The source of the infection was difficult to identify since there were several suspected sources.
A pilot study of presence CSF and PRRS in Uganda was conducted using ELISA and RT-PCR in a cross-sectional study on 239 samples from the district of Rakai in southern Uganda and 80 samples from reported outbreaks of mortality in pigs where ASF virus had not been confirmed as the cause. All samples were negative for CSF and only one sample was seropositive for PRRS. The one positive sample for PRRS was suspected to be a false positive.

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Studien hade två olika syften. Det huvudsakliga syftet var att undersöka dynamiken och effekterna av Afrikansk svinpest (ASF) på en gård i Uganda under ett utbrott genom en fallstudie. Det andra målet var att uppskatta förekomsten av två viktiga differentialdiagnoser av ASF: Klassisk svinpest (CSF) och Porcine Reproduction and Respiratory syndrome (PRRS).

Den fält och laboratoriebaserade fallstudien av dynamiken på gårdsnivå av ASF virus genomfördes med hjälp av intervjuer, ELISA och RT-PCR, under ett pågående utbrott (Oktober-December 2010) på en gård i distriktet Mityana, Uganda. Den ekonomiska effekten av utbrottet på gården uppskattades. Effekterna av utbrottet var djupgående. Gårdsägaren förlorade ungefär hälften av populationen av grisar, främst vuxna och nyfödda grisar. Avvanda grisar och äldre smågrisar överlevde i en relativt sett större utsträckning. Utbrottet spreds mellan boxar och enheter via direkt och indirekt kontakt. Källan till infektionen var svår att identifiera eftersom det fanns flera misstänkta källor av introduktion av smittan till gården.

En pilotstudie av förekomst av CSF och PRRS i Uganda utfördes med ELISA och RT-PCR i en cross-sectional studie med 239 prover från distriktet Rakai i södra Uganda och 80 prover från rapporterade utbrott av dödlighet hos svin där ASF virus inte bekräftats som orsaken. Alla prover var negativa för CSF och endast ett prov var seropositivt för PRRS. Det enda positiva provet för PRRS misstänktes dock vara falskt positivt.

Main title:African swine fever in Uganda
Subtitle:description of a recent outbreak and possible differential diagnoses
Authors:Andersson, Malin
Supervisor:Berg, Mikael and Ståhl, Karl
Examiner:Belak, Sandor
Series:Examensarbete / Sveriges lantbruksuniversitet, Fakulteten för veterinärmedicin och husdjursvetenskap, Veterinärprogrammet
Volume/Sequential designation:2011:34
Year of Publication:2011
Level and depth descriptor:First cycle, G2E
Student's programme affiliation:3050A Veterinary Medicine Programme (admitted before July 1, 2007) 330 HEC
Supervising department:(VH) > Dept. of Biomedical Sciences and Veterinary Public Health
Keywords:African swine fever, Classical swine fever, Porcine Reproductive and Respiratory syndrome, Uganda
URN:NBN:urn:nbn:se:slu:epsilon-s-8
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-s-8
Subject. Use of subject categories until 2023-04-30.:Animal diseases
Language:English
Deposited On:04 Apr 2011 10:51
Metadata Last Modified:20 Apr 2012 14:18

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